K2, also known as “Spice” or “fake weed,” is dried plant material that has been sprayed with various synthetic cannabinoid chemicals. It is not a single drug, and the specific chemical composition can vary widely and unpredictably from one packet to another.
Active Ingredients (Synthetic Cannabinoids)
The main psychoactive chemicals in K2/Spice are laboratory-synthesized cannabinoids, which bind strongly to CB1 and CB2 receptors in the brain. Common examples include:
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JWH-018 – One of the earliest synthetic cannabinoids, highly potent.
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JWH-073 – Similar to JWH-018 but slightly less potent.
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AB-FUBINACA – Found in recent K2 formulations, extremely strong and unpredictable.
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AM-2201 – A powerful full agonist of CB1 receptors.
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HU-210 – Very potent, long-lasting effects, sometimes included in “herbal incense” blends.
⚠️ These compounds are usually more potent than THC, producing stronger psychoactive and adverse effects.
Inactive Ingredients
To deliver the synthetic chemicals, K2/Spice typically contains:
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Dried plant matter – Usually herbs or shredded leaves that act as a carrier.
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Solvents or sprays – Chemicals like acetone or ethanol are used to coat the plant material.
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Unknown additives – Some batches may include flavorings, dyes, or other untested chemicals.
Because the mixture changes frequently, users cannot predict the exact chemical makeup, making K2 highly dangerous.
